Impaired glucose metabolism in the brain of subjects with schizophrenia, these subjects also had lower levles…

Impaired glucose metabolism in the brain of subjects with schizophrenia, these subjects also had lower levles of the PDH complex and higher levels of lactate, indicating low oxidative metabolism.

The brain uses A LOT of energy, mainly in the form of glucose, when it's ability to use glucose and the activity of the krebs cycle declines, mental diseases develop.

[PMID: 27845781]

"This study presents the data that supports the hypothesis that
abnormal striatal glucose metabolism is contributing to the
pathophysiology of schizophrenia. This proportion comes from
our findings of low levels of PDHB and higher levels of pyruvate,
along with a trend to higher…