Histamine is the sleep antagonist.
Anther win for cyproheptadine. blocking histamine and serotonin will - Improve sleep quality - make you happier - enhance cognitive function - nuke brain fog this 74 yo women:
Brain & cognition studies
19 posts on memory, cognition and neurodegeneration. Every post breaks down a real PubMed study and links to the paper.
Histamine is the sleep antagonist.
Anther win for cyproheptadine. blocking histamine and serotonin will - Improve sleep quality - make you happier - enhance cognitive function - nuke brain fog this 74 yo women:
Holy shit taurine: 3g a day for a month was enough to improve cognitive function and memory.
Your vagus nerve is the one delivering messages from your gut to your brain.
He's responsible for parasympathetic nervous system activation. He's the one telling your brain that everything is ok, That the gut is digesting and your environment is beneficial. Sympathetic signals usually run thru the spinal chord. In a metabolic view it's quite parallel to oxidative metabolism with high thyroid and Androgens/Progesterone compared to stress metabolism driven by cortisol and serotonin.
4-7 breaths per minute is a great way to stimulate the vagus nerve and activate the parasympathetic nervous…
This man FIXED his brain fog with taurine.
This amino acid can: • Increase bile acid production. • Lower gut inflammation • Improve insulin sensitivity • Strengthen the gut barrier. If you have brain fog you should also try:
If you have gut issues NEVER choose:
• Omega 3 • Ashwagandha • Low carb diet Instead, choose:
He CURED his depression with sun exposure.
Most depressed people sit in their office most days, they barely look outside and focus on blue screens. Sunlight activates our metabolism, wakes up thousands of genes responsible for mood, cognitive function, strength. The part of the eye that is responsible for converting photons to electric signals (aka retina) ,Has 3-5 times more mitochondria than an average cell. The sun has an insane range of infrared red light which activates energy production in our retina. DOPAMINE production and supply to the brain relies heavily on retinal energy production and sun exposure.
Neurons don't touch. Between every single one of them is a tiny gap, they communicate with electrical signals…
Dopamine is one of those messengers. It's behind why you want things, why you chase things, why achieving something feels good. Every ounce of motivation you've ever felt started dopamine.
Russian smart drugs are kinda crazy.
Bromantane increases the expression of genes responsible for producing Tyrosine hydrolase which is the first and rate limiting enzyme in dopamine synthesis and DOPA decarboxylase which removes the carboxyl group from L-DOPA and yields dopamine. Bromantane enhances cognitive function, increase motivation while lowering prolactin and serotonin. "This leads to a conclusion that the pharmacological activity of Ladasten is related to activation of de novo synthesis of TH and DDC".
A primary neurotoxic agent in Alzheimer's disease, Impaired brain energy metabolism and oxidative stress is…
Known to rise in oxidative stress and to decrease as oxidative metabolism and NAD/NADH increase. This study shows that B3 and nicotinamide mononucleotide (NMN) which is more expensive and not much better than good old Niacinamide is effective in increasing oxidative state and restore NAD levels. Increasing ATP levels and lowering ROS levels.
B2 reverts cognitive decline and neuroinflammation caused by endotoxin(LPS).
FAD (Flavin Adenine Dinucleotide) and FMN (Flavin Mononucleotide) are specialized electron carriers known as flavoproteins, both are produced from B2. 1/6 🧵
Once a brain cell dies, generating a new one in its place is extremely difficult, Neurological disorders like…
This research demonstrates that vitamin B1 prevents the death of brain cells, thus might an effective tool against neurodegeneration.
13 Japanese volunteers got: 100 mg of GABA or 200 mg L-theanine,
Then got their brain waves tested on EEG.
70 obese people with knee osteoarthritis took S.Boulardii and had improved pain intensity, less…
the gut-brain axis is incredible.
Low B1 levels cause oxidative stress and drive neurodegeneration.
Blocking serotonin provided significant pain relief in patients with chronic neuro-inflammatory condition…
years of pain gone.
Impaired glucose metabolism in the brain of subjects with schizophrenia, these subjects also had lower levles…
The brain uses A LOT of energy, mainly in the form of glucose, when it's ability to use glucose and the activity of the krebs cycle declines, mental diseases develop. [PMID: 27845781]
Direct sunlight is crucial for Dopamine synthesis.
A THREAD 🧵
Cortisol causes a significant muscle mass loss.
Found to also be catabolic to the Thymus ,Heart, Liver and spleen, basically toxic to every part of our body. Vitamin D3 on the other hand is protective against cortisol, Completely blocked the atrophy of skeletal muscle mass, Thymus ,Heart ,Liver and spleen. dexamethasone (DEX) is a nasty synthetic glucocorticoid, God knows why but it's a standard protocol to be given to patients with inflammation, edema, certain cancers, autoimmune conditions, allergic reactions, asthma and COVD. Although that it was shown in multiple studies to suppress immunity, cause bone loss, atrophy of basically every tissue that contain amino acids. It comes with no surprise because Cortisol main rule is to maintain Blood Glucose levels during stress and it does so by tearing apart every tissue that contains amino-acid e.g., your brain, muscle, thymus etc. The hero of this study was Vitamin D3, We get it Easily from Cholesterol when we expose our skin to the sun, It completely blocked the nasty effects of DEX. "Vitamin D is considered to be a potent anti-catabolic compound [1,2]. Numerous studies suggest a positive role of vitamin D in sarcopenia prevention" Bad news for the Ice bath lovers, this study also showed that ice bath increase cortisol levels, extreme cold is a stressor so it will trigger cortisol. "As was expected, cold water immersion caused a significant induction of hypothalamic–pituitary–adrenal (HPA) axis activation and a cortisol surge into the blood" Main study PMID: 33799389 PMCID: PMC7998166 DOI: 10.3390/nu13030936 1.PMID: 32699341 2.PMID: 30529188 #vitaminD#cortisol#muscle#liverhealth#bioenergetics
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