Studies

Gut health studies

16 posts on the gut barrier, endotoxin, SIBO, IBS and probiotics. Every post breaks down a real PubMed study and links to the paper.

Sep 26, 2026 · 1 min read Your vagus nerve is the one delivering messages from your gut to your brain. He's responsible for parasympathetic nervous system activation. He's the one telling your brain that everything is ok, That the gut is digesting and your environment is beneficial. Sympathetic signals usually run thru the spinal chord. In a metabolic view it's quite parallel to oxidative metabolism with high thyroid and Androgens/Progesterone compared to stress metabolism driven by cortisol and serotonin.
Sep 22, 2026 · 2 min read This is why your breath stinks (I'll show you how to fix it) Bad breath is not food smell, bacteria from your gut sits inside your mouth and produce some stinky ass compounds. - Volatile sulfur compounds that smell like rotten eggs - Cadaverine which smells like rotten meat - Putrescine which resembles rotten fish - Skatole: formed by tryptophan and smell like shit Follow these 5 steps and the smell will go away 🧵
Sep 15, 2026 · 1 min read 4-7 breaths per minute is a great way to stimulate the vagus nerve and activate the parasympathetic nervous…
Sep 15, 2026 · 1 min read This man FIXED his brain fog with taurine. This amino acid can: • Increase bile acid production. • Lower gut inflammation • Improve insulin sensitivity • Strengthen the gut barrier. If you have brain fog you should also try:
Sep 14, 2026 · 1 min read If you have gut issues NEVER choose: • Omega 3 • Ashwagandha • Low carb diet Instead, choose:
Sep 10, 2026 · 1 min read He CURED his depression with sun exposure. Most depressed people sit in their office most days, they barely look outside and focus on blue screens. Sunlight activates our metabolism, wakes up thousands of genes responsible for mood, cognitive function, strength. The part of the eye that is responsible for converting photons to electric signals (aka retina) ,Has 3-5 times more mitochondria than an average cell. The sun has an insane range of infrared red light which activates energy production in our retina. DOPAMINE production and supply to the brain relies heavily on retinal energy production and sun exposure.
Sep 9, 2026 · 1 min read He SOLVED his adderall addiction with BPC-157. Too many people abuse amphetamine without addressing the root cause of their ADHD. Adderall doesn't give you dopamine. It BORROWS it. That's why the same dose that used to give you laser focus now barely gets you out of bed. Here's the part almost nobody talks about: your dopamine system isn't broken permanently. It's suppressed, and with the right strategy it can be reversed, full article below.
Sep 3, 2026 · 1 min read Psyllium husk increases bowel movements and stool volume. In this study it was used to treat chronic constipation.
Aug 12, 2026 · 1 min read B2 reverts cognitive decline and neuroinflammation caused by endotoxin(LPS). FAD (Flavin Adenine Dinucleotide) and FMN (Flavin Mononucleotide) are specialized electron carriers known as flavoproteins, both are produced from B2. 1/6 🧵
Jul 13, 2026 · 1 min read 70 obese people with knee osteoarthritis took S.Boulardii and had improved pain intensity, less… the gut-brain axis is incredible.
Jul 13, 2026 · 1 min read 72 patients with diarrhea-dominant irritable bowel syndrome enrolled in a study to see if supplementing… The results?
Jul 13, 2026 · 1 min read 100 H.pylori infected patients were randomly divided into two groups to see if supplementing S.Boulardii… 30% of the patients that got S.Boulardii for two weeks had complete eradication of the H.pylori infection.
Jul 13, 2026 · 1 min read 54 patients with SIBO and IBS received S.Boulardii. The results? -less diarrhea -improved digestive symptoms -reduced bacterial overgrowth
Jun 14, 2026 · 1 min read Glycine might be the most anti-inflammatory amino acid. -protects against the effects of endotoxin(LPS) -Inhibit TNF-alpha and superoxide production -Prevents intracellular levels of calcium to rise.
Mar 8, 2026 · 1 min read B1 strengthen the epithelial barrier function, improves gut microbime, lowers endotoxin and alleviate obesity… B1 supports oxidative metabolism of EVERY cell, our Epithelial Layer is formed by 150 Billion cells, so it comes with no surprise that b1 improves the function of this layer. What's even more amazing is that those researchers found it can improve the composition of the gut microbiota, and lower endotoxin LPS production. In this study it was shown to reduce Proteobacteria and Bacteroidetes count. Proteobacteria: Escherichia (E. coli), Salmonella, and Helicobacter, Highly toxic, inflammatory, and can trigger systemic inflammatory conditions, overgrowth of Proteobacteria is strongly associated with increased intestinal permeability and gut dysbiosis. Bacteroidetes: mainly Gram-Negative They have genetic arsenal calles Polysaccharide Utilization Loci (PULs). These allow them to consume highly complex plant fibers and even our glycans (mucus lining), In a balanced state, they are essential for stability, but if the gut barrier is weak, their LPS enter the bloodstream and trigger inflammation, overgrowth of Bacteroidetes is strongly associated with increased intestinal permeability and gut dysbiosis. [PMID: 39990607]
Mar 7, 2026 · 1 min read One of the main ways Endotoxin activates the HPA-axis is by increasing Nitric Oxide production which directly…

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