B1 strengthen the epithelial barrier function, improves gut microbime, lowers endotoxin and alleviate obesity…

B1 strengthen the epithelial barrier function, improves gut microbime, lowers endotoxin and alleviate obesity symptoms .

B1 supports oxidative metabolism of EVERY cell, our Epithelial Layer is formed by 150 Billion cells, so it comes with no surprise that b1 improves the function of this layer.
What's even more amazing is that those researchers found it can improve the composition of the gut microbiota, and lower endotoxin LPS production.

In this study it was shown to reduce Proteobacteria and Bacteroidetes count.

Proteobacteria: Escherichia (E. coli), Salmonella, and Helicobacter, Highly toxic, inflammatory, and can trigger systemic inflammatory conditions, overgrowth of Proteobacteria is strongly associated with increased intestinal permeability and gut dysbiosis.
Bacteroidetes: mainly Gram-Negative They have genetic arsenal calles Polysaccharide Utilization Loci (PULs). These allow them to consume highly complex plant fibers and even our glycans (mucus lining), In a balanced state, they are essential for stability, but if the gut barrier is weak, their LPS enter the bloodstream and trigger inflammation, overgrowth of Bacteroidetes is strongly associated with increased intestinal permeability and gut dysbiosis.
[PMID: 39990607]