Studies

Testosterone & DHT studies

16 posts on testosterone, DHT and androgens. Every post breaks down a real PubMed study and links to the paper.

Sep 28, 2026 · 1 min read Finasteride one shotted him. not only does it nukes your DHT, muscle strength and metabolism, it also doesn’t work in many cases. AVOID! Instead of chemical castration you can choose:
Sep 26, 2026 · 1 min read Your vagus nerve is the one delivering messages from your gut to your brain. He's responsible for parasympathetic nervous system activation. He's the one telling your brain that everything is ok, That the gut is digesting and your environment is beneficial. Sympathetic signals usually run thru the spinal chord. In a metabolic view it's quite parallel to oxidative metabolism with high thyroid and Androgens/Progesterone compared to stress metabolism driven by cortisol and serotonin.
Sep 3, 2026 · 1 min read DHT improves glucose metabolism in diabetic rats, researchers divided them into 3 groups: sedentary…
Aug 31, 2026 · 1 min read Testosterone improves glucose metabolism of hypogonadal men with type 2 diabetes. "We found that TRT could improve glycemic control and decrease triglyceride levels of hypogonadal men with type 2 diabetes mellitus"
Jul 28, 2026 · 1 min read Prostate cancer is one of the most frequently diagnosed malignancies in men. Androgen deprivation therapy (ADT) is the first-line treatment and fundamental management for men with advanced PCa to suppress functions of androgen/androgen receptor (AR) signaling. Those men develop metabolic syndrome once DHT gets nuked.
Jul 28, 2026 · 1 min read Androgen receptor is a crucial factor in glucose oxidation.
Jul 27, 2026 · 1 min read They tested the levels of DHT in 852 men. Then divided them into 3 group: Low DHT, Average DHT, High DHT and tested Testosterone,SHBG,glucose,insulin and triglycerids.
Jul 15, 2026 · 1 min read 16 overweight women with PCOS were put on ketogenic diet for 12 weeks, this is truly evil in my opinion but…
Jul 13, 2026 · 1 min read 9 infertile men enrolled in a study, they got 400mg vitamin E and 100 micro-gram selenium daily for six… the results? -sperm motility tripled -sperm morphology doubled -live sperm cells doubled -Glutathione Peroxidase increased, indicating less oxidative stress.
Jul 8, 2026 · 1 min read In this study 2000 IU vitamin D3 was given for 2 weeks to people to test if it lowers cortisol levels, the results?
Jun 30, 2026 · 1 min read People with high blood pressure have lower blood volume than healthy people.
Jun 24, 2026 · 1 min read Mice on high fat diet became obese and developed glucose intolerance, high fat diet affected 102 proteins in…
Jun 24, 2026 · 1 min read Tadalafil is associated with increased testosterone/estradiol ration, which also means higher DHT levels…
Jun 24, 2026 · 1 min read B1 raises testosterone and creates stronger wood.
Jun 22, 2026 · 1 min read DHT is a powerful anti cortisol agent, improves sperm production, modulates CRH gene expression.
Mar 1, 2026 · 2 min read A systematic review on the role of aromatase inhibitors for men with prolactinoma and hypogonadism shows that… A combination of Androgen(DHT/T) + Aromatase inhibitor(Examastane) + Dopamine agonist(Bromocriptine) can be VERY powerful in lowering prolactin and estrogen. "In 2002, Gillam and colleagues reported on a case of a 34-year-old male patient with a macroprolactinoma and low testosterone levels; the patient responded to cabergoline treatment with significant reduction in prolactin levels, from 10,362 μf/L to 61 μg/L. However, as symptoms of hypogonadism persisted, testosterone was added, followed by an increase in prolactin levels, which came back down following the discontinuation of testosterone. A combination of cabergoline with anastrozole (1 mg daily) and a testosterone treatment resulted in improved clinical symptoms without increasing prolactin levels. Interestingly, at attempt to discontinue the anastrozole to determine the effect of anastrozole on prolactin levels resulted in an immediate spike in the prolactin levels, with a subsequent decline after re-introducing the aromatase inhibitor. The authors concluded that the addition of an aromatase inhibitor allowed for the continued use of testosterone as it prevented the testosterone-induced prolactin increase and potential tumor enlargement. Furthermore, the combination of an aromatase inhibitor with a dopamine agonist resulted in prolactin levels that were lower than those recorded at any other time point," "Lima and colleagues reported on a 29-year-old man with hyperprolactinemia exacerbated by testosterone replacement therapy. The patient was diagnosed with a giant prolactinoma and achieved normal serum prolactin levels with cabergoline. However, as symptoms of hypogonadism persisted, testosterone replacement therapy was initiated, followed by a more than six-fold increase in prolactin levels. Adding letrozole (2.5 mg daily) treatment was associated with a significant reduction in prolactin levels " A much better option than testosterone would be DHT, which can't be aromatised to estrogen, also exemestane was shown to be much safer in blocking aromatase, this shows that combination of Androgen + Aromatase inhibitor + Dopamine agonist can be VERY powerful in lowering prolactin and estrogen. [PMID: 36835974]

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