Ray Peat: Prostate Cancer

Estrogen, dysplasia, and the Noble rat

1. Selective increase in type II estrogen-binding sites in the dysplastic dorsolateral prostates of noble ratsCancer Res · 1993 · PMID 7678774
2. Suppression of testosterone and estradiol-17beta-induced dysplasia in the dorsolateral prostate of Noble rats by bromocriptineCarcinogenesis · 1997 · PMID 9276623
3. Development and restitution of squamous metaplasia in the calf prostate after a single estrogen treatment. An electron microscopic studyExp Mol Pathol · 1972 · PMID 5029933
4. Hormone levels in prostatic fluid from healthy finns and prostate cancer patientsEur J Cancer Clin Oncol · 1984 · PMID 6541586
5. 17 beta-estradiol stimulates a rapid Ca2+ influx in LNCaP human prostate cancer cellsEur J Endocrinol · 1996 · PMID 8890730 · cited in Estrogen Receptors -- what do they explain?
6. Age related changes in free plasma testosterone, dihydrotestosterone and oestradiolActa Endocrinol (Copenh) · 1975 · PMID 1173981

Prolactin, pituitary, and growth factors

1. Prolactin and prolactin receptors are expressed and functioning in human prostateJ Clin Invest · 1997 · PMID 9045863
2. Transgenic mice overexpressing the prolactin gene develop dramatic enlargement of the prostate glandEndocrinology · 1997 · PMID 9322957
3. Effects of pituitary grafts on testosterone stimulated growth of rat prostateBiol Reprod · 1980 · PMID 7378539
4. Dietary fat and protein intake differ in modulation of prostate tumor growth, prolactin secretion and metabolism, and prostate gland prolactin binding capacity in ratsJ Nutr · 1997 · PMID 9039822
5. Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell cultureCancer Res · 1984 · PMID 6370422
6. Inhibition of in vivo proliferation of androgen-independent prostate cancers by an antagonist of growth hormone-releasing hormoneBr J Cancer · 1997 · PMID 9184172

Androgen, survival, and anti-androgen history

1. Carcinoma of the prostate: relationship of pretreatment hormone levels to survivalEur J Cancer Clin Oncol · 1984 · PMID 6426967
2. Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasterideProc Natl Acad Sci U S A · 1996 · PMID 8876218
3. The induction of NB rat prostatic carcinomasAnticancer Res · 1984 · PMID 6486730

Ovary spleen, prostaglandins, desmoid, aging gland

1. Gonadotropin-releasing hormone agonist suppression of ovarian tumorigenesis in mice of the Wx/Wv genotypeBiol Reprod · 1995 · PMID 8547469
2. Profiles of prostaglandin biosynthesis in sixteen established cell lines derived from human lung, colon, prostate, and ovarian tumorsCancer Res · 1988 · PMID 3409218
3. Regression of large pelvic desmoid tumor by tamoxifen and sulindacUrology · 1996 · PMID 8650880
4. Age-related changes of the prostate gland in the senescence-accelerated mouseProstate · 1994 · PMID 7507239

More references from this article

1. The effect of cyproterone acetate on advanced carcinoma of the prostateSurg Gynecol Obstet · 1968 · PMID 5675191
2. Effect of cyproterone acetate on clinical, endocrine and pathological features of benign prostatic hypertrophyJ Steroid Biochem · 1975 · PMID 1177427
3. Effect of the addition of estrogen to medical castration on prostatic size, symptoms, histology and serum prostate specific antigen in 4 men with benign prostatic hypertrophyJ Urol · 1991 · PMID 1714969
4. Hormonal pattern in prostatic cancer. I. Correlation with local extent of tumour, presence of metastases and grade of differentiationActa Endocrinol (Copenh) · 1981 · PMID 7304085
5. Prostaglandin in human breast cancer: Evidence suggesting that an elevated prostaglandin production is a marker of high metastatic potential for neoplastic cellsJ Natl Cancer Inst · 1980 · PMID 6767871
6. Epidemiologic study of prostatic cancer: preliminary reportCancer Treat Rep · 1977 · PMID 194689
7. Bimodal age-frequency distribution of epitheliosis in cancer mastectomies: relevance to preneoplasiaCancer · 1982 · PMID 7139535
8. An atlas of subgross pathology of the human breast with special reference to possible precancerous lesionsJ Natl Cancer Inst · 1975 · PMID 169369
9. HORMONAL FACTORS IN THE ADRENAL-DEPENDENT GROWTH OF THE RAT VENTRAL PROSTATENatl Cancer Inst Monogr · 1963 · PMID 14072993
10. Testosterone secretion and metabolism in male senescenceJ Clin Endocrinol Metab · 1972 · PMID 5012774
11. Abnormal levels of plasma hormones in men with prostate cancer: evidence toward a "two-disease" theoryProstate · 1982 · PMID 7155990
12. Non-genomic steroid action--take a closer look, it's not rare! An invited commentaryEur J Endocrinol · 1996 · PMID 8890717