Ray Peat on Vitamins A, D and K
Short answer: Ray Peat gave each of the fat-soluble vitamins a job in his system. Vitamin A feeds the making of the protective steroid hormones, vitamin D with calcium keeps parathyroid hormone quiet, and vitamin K supports cell respiration and directs calcium into bone.
What Ray Peat wrote about vitamins a, d and k
Vitamin A is used heavily in steroid synthesis. He suspected it is needed for the step that turns cholesterol into pregnenolone, and noted that a progesterone supplement can prevent the symptoms of vitamin A deficiency. Source: Multiple Sclerosis and other hormone related brain syndromes
Vitamin A is needed for the proper differentiation of skin and other linings. A deficiency releases enzymes that break tissue down. Source: Blocking Tissue Destruction ↗
Thyroid hormone and vitamin A travel on the same carrier protein. Polyunsaturated fats compete for it and block the effects of both. Source: Fats, functions & malfunctions
He names thyroid, adequate animal protein, trace minerals and vitamin A as the first things to consider for preventing prostate enlargement. Source: Prostate Cancer
Vitamin D and vitamin K are both now known to prevent diabetes. Enough calcium and vitamin D keep parathyroid hormone suppressed, which he considered important against the degenerative diseases. Source: Glucose and sucrose for diabetes
Vitamin K is needed for the step in which carbon dioxide is built into osteocalcin so that it can bind calcium. Like aspirin, it supports cell respiration and inhibits lactic acid formation. Source: Osteoporosis, aging, tissue renewal, and product science
Antibiotics, and the natural antibiotics in raw carrot, can reduce the gut bacteria that make vitamin K, so he advised supplying it. Source: Rosacea, inflammation, and aging: The inefficiency of stress
Calcium, magnesium, vitamin A, vitamin B6, vitamin K and vitamin D are his list for developing and maintaining bone. Source: Bone Density: First Do No Harm
What he suggested in practice
- Liver about once a week as the food source of vitamin A.
- Not cod liver oil, because of its unsaturated fat.
- Calcium carbonate with vitamins D and K for a quick anti-stress effect.
- Vitamin K, or occasional liver or broccoli, when eating raw carrot daily or using antibiotics.
Where he wrote about it
This topic comes up in 40 of the articles on his site. These are the most relevant ones:
- Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy · original on raypeat.com ↗
- Sugar issues · original on raypeat.com ↗
- Glucose and sucrose for diabetes · original on raypeat.com ↗
- Vitamin E: Estrogen antagonist, energy promoter, and anti-inflammatory · original on raypeat.com ↗
- Rosacea, inflammation, and aging: The inefficiency of stress · original on raypeat.com ↗
- Alzheimer's: The problem of Alzheimer's disease as a clue to immortality — part 2 · original on raypeat.com ↗
- Blocking Tissue Destruction ↗ · original on raypeat.com ↗
- Milk in context: allergies, ecology, and some myths · original on raypeat.com ↗
My take
In the studies I have covered, 2,000 IU of vitamin D3 lowered cortisol within two weeks, and D3 with K2 beat either one alone for bone density. I get most of my vitamin D from the sun.
Quick answers
What did Ray Peat say about vitamin A?
That it is consumed in making the steroid hormones, probably at the step from cholesterol to pregnenolone, and is needed for healthy skin and linings.
What did Ray Peat say about vitamin D?
That with calcium it keeps parathyroid hormone suppressed, protects bone and helps prevent diabetes.
What did Ray Peat say about vitamin K?
That it supports cell respiration, is needed for osteocalcin to bind calcium in bone, and should be supplied when antibiotics or daily raw carrot reduce the bacteria that make it.
21 studies Ray Peat cited on vitamins a, d and k
- Effect of retinoid (vitamin A or retinoic acid) treatment (hormonal imprinting) through breastmilk on the glucocorticoid receptor and estrogen receptor binding capacity of the adult rat offspringHum Exp Toxicol · 1998 · PMID 9821019 · cited in Estrogen, memory and heredity: Imprinting and the stress response
- A longitudinal study of serum 25-hydroxyvitamin D and intact parathyroid hormone levels indicate the importance of vitamin D and calcium homeostasis regulation in multiple sclerosisJ Neurol Neurosurg Psychiatry · 2008 · PMID 17578859 · cited in Milk in context: allergies, ecology, and some myths
- Diurnal rhythm of plasma 1,25-dihydroxyvitamin D and vitamin D-binding protein in postmenopausal women: relationship to plasma parathyroid hormone and calcium and phosphate metabolismEur J Endocrinol · 2002 · PMID 11980618 · cited in Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy
- Progesterone and vitamin D: Improvement after traumatic brain injury in middle-aged ratsHorm Behav · 2013 · PMID 23896206 · cited in The dark side of stress (learned helplessness)
- Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional studyCardiovasc Diabetol · 2009 · PMID 19187564 · cited in Milk in context: allergies, ecology, and some myths
- The effect of vitamin K supplementation on biochemical markers of bone formation in children and adolescents with cystic fibrosisEur J Pediatr · 2006 · PMID 16622660 · cited in Glucose and sucrose for diabetes
- Inhibitory effect of menaquinone-7 (vitamin K2) on the bone-resorbing factors-induced bone resorption in elderly female rat femoral tissues in vitroMol Cell Biochem · 2003 · PMID 12708750 · cited in Osteoporosis, aging, tissue renewal, and product science
- A calcium-deficient diet caused decreased bone mineral density and secondary elevation of estrogen in aged male rats-effect of menatetrenone and elcatoninMetabolism · 2002 · PMID 12370839 · cited in Milk in context: allergies, ecology, and some myths
- Cellular distribution of retinoic acid receptor-alpha protein in serous adenocarcinomas of ovarian, tubal, and peritoneal origin: comparison with estrogen receptor statusAm J Pathol · 1998 · PMID 9708807 · cited in Estrogen Receptors -- what do they explain?
- Acceleration of experimental diabetic retinopathy in the rat by omega-3 fatty acidsDiabetologia · 1996 · PMID 8721768 · cited in Glycemia, starch, and sugar in context
- Vitamin K status and bone mass in women with and without aortic atherosclerosis: a population-based studyCalcif Tissue Int · 1996 · PMID 8849401 · cited in Osteoporosis, harmful calcification, and nerve/muscle malfunctions
- Regulation of parathyroid hormone and vitamin D in essential hypertensionAm J Hypertens · 1995 · PMID 8845076 · cited in Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy, Milk in context: allergies, ecology, and some myths
- Supplementation with beta-carotene in vivo and in vitro does not inhibit low density lipoprotein oxidationAtherosclerosis · 1995 · PMID 7772078 · cited in Unsaturated Vegetable Oils: Toxic
- Vitamin A and related essential nutrients in cord blood: relationships with anthropometric measurements at birthEarly Hum Dev · 1994 · PMID 7712952 · cited in Vitamin E: Estrogen antagonist, energy promoter, and anti-inflammatory
- Diurnal variations in the electroretinographic c-wave and retinal melatonin content in rats with inherited retinal dystrophyDoc Ophthalmol · 1992 · PMID 1591968 · cited in Aging Eyes, Infant Eyes, and Excitable Tissues
- Oxygen-induced retinopathy in the rat: hemorrhages and dysplasias may lead to retinal detachmentCurr Eye Res · 1992 · PMID 1451526 · cited in Aging Eyes, Infant Eyes, and Excitable Tissues
- Retinoic acid acts synergistically with 1,25-dihydroxyvitamin D3 or antioestrogen to inhibit T-47D human breast cancer cell proliferationJ Steroid Biochem Mol Biol · 1991 · PMID 1654997 · cited in A Physiological Approach to Ovarian Cancer
- Effect of bright light in the hospital nursery on the incidence of retinopathy of prematurityN Engl J Med · 1985 · PMID 3839567 · cited in Aging Eyes, Infant Eyes, and Excitable Tissues
- Respiratory alkalosis and reduced plasmatic concentration of ionized calcium in rats treated with 1,25 dihydroxycholecalciferolCalcif Tissue Int · 1984 · PMID 6098355 · cited in Bone Density: First Do No Harm
- Elevated thrombocyte calcium content in uremia and its correction by 1 alpha(OH) vitamin D treatmentNephron · 1982 · PMID 7099335 · cited in Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy
- Relation of vitamin A deficiency and estrogen to induction of keratinizing metaplasia in the uterus of the ratAm J Clin Nutr · 1957 · PMID 13487534 · cited in A Physiological Approach to Ovarian Cancer
Not affiliated with raypeat.com. This page describes Ray Peat's published articles in our own words and links to the originals. Educational content, not medical advice.