Ray Peat on Iron
Short answer: Ray Peat called iron a potentially toxic heavy metal. He wrote that it builds up in the tissues with age, reacts with unsaturated fats to destroy cells, and that most people should worry about getting too much, not too little.
What Ray Peat wrote about iron
He wrote that iron in excess can cause cancer, heart disease and other illnesses. Source: Iron's Dangers
Iron accumulates in tissues with aging. He connected that to the low-energy state of the cell, which retains both iron and calcium and produces age pigment. Source: Multiple Sclerosis and other hormone related brain syndromes, Aging Eyes, Infant Eyes, and Excitable Tissues
The damage comes from its reaction with unsaturated fats under stress, producing lipid peroxides. Source: Aging Eyes, Infant Eyes, and Excitable Tissues, Mitochondria and mortality
High body iron stores go with more atherosclerosis. Source: Cholesterol, longevity, intelligence, and health
Iron destroys vitamin E, so the vitamin E requirement rises with iron intake and with age. Source: Iron's Dangers
He warned about iron added to food, which destroys vitamins in the food and can be toxic itself, and about iron from cookware, especially with acidic sauces. Source: Iron's Dangers
Milk is naturally low in iron, because the newborn arrives with a large store. He treats that as normal, not as a defect of milk. Source: Milk in context: allergies, ecology, and some myths
What he suggested in practice
- Drink coffee with iron-rich meals. He writes that he always tries to have coffee with meat.
- About 100 units of vitamin E a day, not at the same moment as iron-rich food.
- Avoid iron supplements and iron-fortified foods unless there is a real need.
- Cook in glass or good stainless steel.
- Less unsaturated fat makes the iron you have less harmful.
Where he wrote about it
This topic comes up in 31 of the articles on his site. These are the most relevant ones:
- Iron's Dangers · original on raypeat.com ↗
- Alzheimer's: The problem of Alzheimer's disease as a clue to immortality — part 2 · original on raypeat.com ↗
- Osteoporosis, harmful calcification, and nerve/muscle malfunctions · original on raypeat.com ↗
- Cholesterol, longevity, intelligence, and health · original on raypeat.com ↗
- Multiple sclerosis, protein, fats, and progesterone · original on raypeat.com ↗
- Diabetes, scleroderma, oils and hormones · original on raypeat.com ↗
- Aging Eyes, Infant Eyes, and Excitable Tissues · original on raypeat.com ↗
- Milk in context: allergies, ecology, and some myths · original on raypeat.com ↗
Quick answers
What did Ray Peat say about iron?
That it is a potentially toxic heavy metal that accumulates with age and reacts with unsaturated fats, contributing to cancer, heart disease and aging.
How did Ray Peat reduce iron absorption?
By drinking coffee with iron-rich meals such as meat, avoiding fortified foods and supplements, and taking vitamin E.
21 studies Ray Peat cited on iron
- Increased release of ferritin and iron by iron-loaded alveolar macrophages in cigarette smokersAm J Respir Crit Care Med · 1994 · PMID 8087339 · cited in Iron's Dangers
- Iron released from transferrin at acidic pH can catalyse the oxidation of low density lipoproteinFEBS Lett · 1994 · PMID 7925932 · cited in Iron's Dangers
- Complex I, iron, and ferritin in Parkinson's disease substantia nigraAnn Neurol · 1994 · PMID 7998774 · cited in Iron's Dangers
- CXCR3-B can mediate growth-inhibitory signals in human renal cancer cells by down-regulating the expression of heme oxygenase-1J Biol Chem · 2010 · PMID 20855888 · cited in The Cancer Matrix
- Heme oxygenase-1 in tumor biology and therapyCurr Drug Targets · 2010 · PMID 20704546 · cited in The Cancer Matrix
- Induction of inducible nitric oxide synthase and heme oxygenase-1 in rat glial cellsLife Sci · 1998 · PMID 9585163 · cited in The dark side of stress (learned helplessness)
- Body iron stores and the risk of carotid atherosclerosis: prospective results from the Bruneck studyCirculation · 1997 · PMID 9396420 · cited in Cholesterol, longevity, intelligence, and health
- Iron deposits in multiple sclerosis and Alzheimer's disease brainsBrain Res · 1997 · PMID 9237552 · cited in Multiple sclerosis, protein, fats, and progesterone
- The effect of iron status on glyceraldehyde 3-phosphate dehydrogenase expression in rat liverFEBS Lett · 1995 · PMID 7867783 · cited in Alzheimer's: The problem of Alzheimer's disease as a clue to immortality — part 2
- Effects of magnesium and iron on lipid peroxidation in cultured hepatocytesMol Cell Biochem · 1995 · PMID 7623785 · cited in Alzheimer's: The problem of Alzheimer's disease as a clue to immortality — part 2
- Corticosterone regulates heme oxygenase-2 and NO synthase transcription and protein expression in rat brainJ Neurochem · 1994 · PMID 7519667 · cited in Estrogen — Age Stress Hormone
- Catechol adrenergic agents enhance hydroxyl radical generation in xanthine oxidase systems containing ferritin: implications for ischemia/reperfusionArch Biochem Biophys · 1994 · PMID 7986063 · cited in Iron's Dangers
- Lipid peroxidation in iron deficiency anemiaActa Haematol · 1994 · PMID 8091940 · cited in Iron's Dangers
- Iron delocalization occurs during ischemia and persists on reoxygenation of skeletal muscleJ Lab Clin Med · 1994 · PMID 8083587 · cited in Iron's Dangers
- Iron, magnesium and ischaemic heart diseaseProc Nutr Soc · 1994 · PMID 7886058 · cited in Iron's Dangers
- Mild iron overload effect on rat liver nucleiToxicology · 1994 · PMID 7974509 · cited in Iron's Dangers
- Body iron stores and presence of carotid atherosclerosis. Results from the Bruneck StudyArterioscler Thromb · 1994 · PMID 7918313 · cited in Iron's Dangers
- Dietary fructose or starch: effects on copper, zinc, iron, manganese, calcium, and magnesium balances in humansAm J Clin Nutr · 1989 · PMID 2729168 · cited in Sugar issues
- Perivascular iron deposition and other vascular damage in multiple sclerosisJ Neurol Neurosurg Psychiatry · 1988 · PMID 3346691 · cited in Multiple sclerosis, protein, fats, and progesterone
- Influence of iron on in vivo proliferation and lethality of L1210 cellsJ Nutr · 1985 · PMID 3973748 · cited in Iron's Dangers, A Physiological Approach to Ovarian Cancer
- Inhibition of autoimmune neuropathological process by treatment with an iron-chelating agentJ Exp Med · 1984 · PMID 6333485 · cited in Multiple sclerosis, protein, fats, and progesterone
Not affiliated with raypeat.com. This page describes Ray Peat's published articles in our own words and links to the originals. Educational content, not medical advice.