Ray Peat

Ray Peat on Blood Pressure

By OxidativeState · · 47 articles · 78 studies

Short answer: Ray Peat argued that high blood pressure is usually a problem of too little blood volume, not too much salt. He connected it to low sodium, low calcium, high parathyroid hormone, low thyroid function and the loss of carbon dioxide.

What Ray Peat wrote about blood pressure

He cites the finding that plasma volume is usually lower in people with essential hypertension than in healthy people. The body is short of circulating fluid while the tissues hold edema. Source: Salt, energy, metabolic rate, and longevity, When energy fails: Edema, heart failure, hypertension, sarcopenia, etc

Sodium helps keep water and albumin inside the blood vessels, which maintains blood volume. Source: When energy fails: Edema, heart failure, hypertension, sarcopenia, etc

According to a review of about 100 studies that he cites, salt restriction lowers blood pressure by only a few points, while it raises adrenaline and aldosterone. Source: Salt, energy, metabolic rate, and longevity, When energy fails: Edema, heart failure, hypertension, sarcopenia, etc

He traced the low-salt doctrine to the marketing of thiazide diuretics in the late 1950s. Source: Water: swelling, tension, pain, fatigue, aging

He linked hypertension to the parathyroid glands. Parathyroid activity is raised in essential hypertension, and the hormone causes loss of fluid, which he ties to a leak of calcium in the urine. Source: Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy

Added salt lowered blood pressure in women with toxemia of pregnancy. Source: Salt, energy, metabolic rate, and longevity

Caffeine's effect on blood pressure is slight and may not occur with normal use of coffee. Source: Caffeine: A vitamin-like nutrient, or adaptogen. Questions about tea and coffee, cancer and other degenerative diseases, and the hormones

Poor circulation, he wrote, is what damages the kidneys in hypertension, and that can lead on to heart failure. Source: Water: swelling, tension, pain, fatigue, aging

What he suggested in practice

  • A high protein diet with a little extra salt, which he says usually helps edema, poor circulation and high blood pressure.
  • Enough calcium and vitamin D to keep parathyroid hormone suppressed.
  • Breathing into a paper bag for a minute or two to raise carbon dioxide, which he suggests for lowering blood pressure.
  • Calcium carbonate with vitamins D and K, which he says can sometimes relieve hypertension quickly.
  • High blood pressure is a medical condition. Work with your doctor.

Where he wrote about it

This topic comes up in 47 of the articles on his site. These are the most relevant ones:

My take

I covered a study showing that people with high blood pressure have a lower blood volume than healthy people. I think raising calcium, sodium, potassium and magnesium intake helps, and I wrote about blood volume in Blood volume and vasodilation factors.

Quick answers

What did Ray Peat say causes high blood pressure?

Low blood volume together with edema, driven by low sodium and calcium, high parathyroid hormone, low thyroid function and stress hormones, not by eating salt.

Did Ray Peat say salt raises blood pressure?

No. He wrote that salt restriction lowers blood pressure by only a few points while raising adrenaline and aldosterone, and that added salt lowered blood pressure in toxemia of pregnancy.

78 studies Ray Peat cited on blood pressure

  1. [Hemodynamic and hemorheologic findings in patients with pregnancy-induced hypertension: comparison of pre-eclampsia and chronic hypertension]Klin Wochenschr · 1990 · PMID 2376951 · cited in Bleeding, clotting, cancer
  2. Effects of dairy products on intracellular calcium and blood pressure in adults with essential hypertensionJ Am Coll Nutr · 2009 · PMID 19828899 · cited in Milk in context: allergies, ecology, and some myths
  3. PAI-1 in human hypertension: relation to hypertensive groupsAm J Hypertens · 2002 · PMID 12160190 · cited in Salt, energy, metabolic rate, and longevity
  4. U46619-mediated vasoconstriction of the fetal placental vasculature in vitro in normal and hypertensive pregnanciesJ Hypertens · 1999 · PMID 10100077 · cited in Thyroid, insomnia, and the insanities: Commonalities in disease
  5. Novel appearance of placental nuclear monoamine oxidase: biochemical and histochemical evidence for hyperserotonomic state in preeclampsia-eclampsiaAm J Obstet Gynecol · 1996 · PMID 8987939 · cited in Thyroid, insomnia, and the insanities: Commonalities in disease
  6. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive ratsBiosci Biotechnol Biochem · 1995 · PMID 7539642 · cited in Serotonin: Effects in disease, aging and inflammation
  7. Blindness associated with preeclampsia and eclampsiaAm J Obstet Gynecol · 1995 · PMID 7726272 · cited in Bleeding, clotting, cancer
  8. Ambulatory blood pressure in mild hypertensive women taking oral contraceptives. A case-control studyAm J Hypertens · 1995 · PMID 7794573 · cited in Progesterone, not estrogen, is the coronary protection factor of women
  9. Dietary calcium reduces blood pressure, parathyroid hormone, and platelet cytosolic calcium responses in spontaneously hypertensive ratsAm J Hypertens · 1994 · PMID 7702798 · cited in Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy
  10. Dietary calcium and blood pressure in experimental models of hypertension. A reviewHypertension · 1994 · PMID 8144221 · cited in Milk in context: allergies, ecology, and some myths
  11. Effects of alpha-tocopherol and tocotrienols on blood pressure and linoleic acid metabolism in the spontaneously hypertensive rat (SHR)Biosci Biotechnol Biochem · 1992 · PMID 1368948 · cited in Vitamin E: Estrogen antagonist, energy promoter, and anti-inflammatory
  12. Salt restriction lowers resting blood pressure but not 24-h ambulatory blood pressureAm J Hypertens · 1991 · PMID 2069774 · cited in Salt, energy, metabolic rate, and longevity
  13. Effect of high calcium diet on magnesium, catecholamines, and blood pressure of stroke-prone spontaneously hypertensive ratsProc Soc Exp Biol Med · 1988 · PMID 3353396 · cited in Osteoporosis, aging, tissue renewal, and product science
  14. Effects of calcium infusion on blood pressure in hypertensive and normotensive humansHypertension · 1986 · PMID 3011665 · cited in Calcium and Disease: Hypertension, organ calcification, & shock, vs. respiratory energy
  15. Studies on plasma fibrinogen level in pre-eclampsia and eclampsiaExperientia · 1978 · PMID 658223 · cited in Eclampsia in the Real Organism: A Paradigm of General Distress Applicable in Infants, Adults, Etc
  16. Pharmacological inhibition of inducible nitric oxide synthase (iNOS) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, convalesce behavior and biochemistry of hypertension induced vascular dementia in ratsPharmacol Biochem Behav · 2013 · PMID 23201648 · cited in The dark side of stress (learned helplessness)
  17. Aspirin attenuates pulmonary arterial hypertension in rats by reducing plasma 5-hydroxytryptamine levelsCell Biochem Biophys · 2011 · PMID 21327581 · cited in Osteoporosis, aging, tissue renewal, and product science
  18. Milk products, dietary patterns and blood pressure managementJ Am Coll Nutr · 2009 · PMID 19571168 · cited in Milk in context: allergies, ecology, and some myths
  19. Dietary salt restriction increases plasma lipoprotein and inflammatory marker concentrations in hypertensive patientsAtherosclerosis · 2008 · PMID 18262533 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  20. Hepatic effects of a fructose diet in the stroke-prone spontaneously hypertensive ratAm J Hypertens · 2008 · PMID 18437120 · cited in Sugar issues
  21. Maternal-fetal metabolism in normal pregnancy and preeclampsiaFront Biosci · 2007 · PMID 17127255 · cited in Salt, energy, metabolic rate, and longevity
  22. Pre-eclampsia and hyponatraemiaJ Obstet Gynaecol · 2006 · PMID 17071447 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  23. Increased sympathetic activity present in early hypertensive pregnancy is not lowered by plasma volume expansionHypertens Pregnancy · 2006 · PMID 17065036 · cited in Salt, energy, metabolic rate, and longevity
  24. Effect of serotonin on respiration, cerebral circulation, and blood pressure in ratsBull Exp Biol Med · 2005 · PMID 16142278 · cited in Serotonin: Effects in disease, aging and inflammation
  25. Changes in lipid metabolism and antioxidant defense status in spontaneously hypertensive rats and Wistar rats fed a diet enriched with fructose and saturated fatty acidsNutrition · 2005 · PMID 15723754 · cited in Sugar issues
  26. The effects of drinks made from simple sugars on blood pressure in healthy older peopleBr J Nutr · 2005 · PMID 15975155 · cited in Salt, energy, metabolic rate, and longevity
  27. Severe hyponatraemia and pre-eclampsiaBJOG · 2004 · PMID 15327622 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  28. Augmented PLA2 activity in pre-eclamptic decidual tissue--a key player in the pathophysiology of 'acute atherosis' in pre-eclampsia?Placenta · 2003 · PMID 14580379 · cited in Fats and degeneration
  29. Moderate sodium restriction enhances the pressor response to hyperlipidemia in obese, hypertensive patientsJ Clin Hypertens (Greenwich) · 2002 · PMID 12045366 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  30. Effect of renin-angiotensin system activation by dietary sodium restriction and upright position on plasma leptin concentration in patients with essential hypertensionMed Sci Monit · 2002 · PMID 12118193 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  31. Salt supresses baseline muscle sympathetic nerve activity in salt-sensitive and salt-resistant hypertensivesJ Hum Hypertens · 2002 · PMID 12522465 · cited in Salt, energy, metabolic rate, and longevity
  32. Melatonin potentiates NE-induced vasoconstriction without augmenting cytosolic calcium concentrationAm J Physiol Heart Circ Physiol · 2001 · PMID 11123259 · cited in Water: swelling, tension, pain, fatigue, aging
  33. Ketanserin versus dihydralazine in the management of severe early-onset preeclampsia: maternal outcomeAm J Obstet Gynecol · 1999 · PMID 9988803 · cited in Thyroid, insomnia, and the insanities: Commonalities in disease
  34. Importance of dietary calcium in hypertensionJ Am Coll Nutr · 1998 · PMID 9477397 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  35. Dilutional hyponatremia in pre-eclampsiaAm J Obstet Gynecol · 1998 · PMID 9822522 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  36. Reduction of capillary permeability in the fructose-induced hypertensive ratAm J Hypertens · 1998 · PMID 9633792 · cited in Sugar issues
  37. Free fatty acid fractions from some vegetable oils exhibit reduced survival time-shortening activity in stroke-prone spontaneously hypertensive ratsLipids · 1998 · PMID 9688167 · cited in The Great Fish Oil Experiment
  38. Serotonin inhibition of 1-methylxanthine metabolism parallels its vasoconstrictor activity and inhibition of oxygen uptake in perfused rat hindlimbActa Physiol Scand · 1997 · PMID 9366958 · cited in Osteoporosis, aging, tissue renewal, and product science
  39. Unusual effects of some vegetable oils on the survival time of stroke-prone spontaneously hypertensive ratsLipids · 1997 · PMID 9252963 · cited in The Great Fish Oil Experiment
  40. Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsiaLancet · 1997 · PMID 9357405 · cited in Thyroid, insomnia, and the insanities: Commonalities in disease

Showing 40 of 78. Search all of them in the database →

Not affiliated with raypeat.com. This page describes Ray Peat's published articles in our own words and links to the originals. Educational content, not medical advice.

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