Ray Peat: Protective CO2 and aging

CO2 as antioxidant and anti-excitatory gas

1. [Carbon dioxide--a universal inhibitor of the generation of active oxygen forms by cells (deciphering one enigma of evolution)]Izv Akad Nauk Ser Biol · 1997 · PMID 9190222 · cited in Genes, Carbon Dioxide and Adaptation
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3. [Ability of carbon dioxide to inhibit generation of superoxide anion radical in cells and its biomedical role]Vopr Med Khim · 1996 · PMID 9139450
4. Carbon dioxide protects the perinatal brain from hypoxic-ischemic damage: an experimental study in the immature ratPediatrics · 1995 · PMID 7761212 · cited in Alzheimer's: The problem of Alzheimer's disease as a clue to immortality — part 1
5. Effect of carbon dioxide on cerebral metabolism during hypoxia-ischemia in the immature ratPediatr Res · 1997 · PMID 9212033
6. Effect of acidotic challenges on local depolarizations evoked by N-methyl-D-aspartate in the rat striatumLife Sci · 1997 · PMID 9247322

Uncoupling, denervation, methionine, methylation

1. Uncoupling protein-2 regulates lifespan in miceAm J Physiol Endocrinol Metab · 2009 · PMID 19141680
2. Respiratory uncoupling in skeletal muscle delays death and diminishes age-related diseaseCell Metab · 2007 · PMID 18054318
3. Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS productionAm J Physiol Regul Integr Comp Physiol · 2007 · PMID 17584954
4. Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heartJ Bioenerg Biomembr · 2009 · PMID 19633937

Altitude, bicarbonate, sleep CO2

1. [Adaptation to high altitude hypoxia facilitates a limitation of lipid peroxidation activation in inflammation and stress]Biull Eksp Biol Med · 1995 · PMID 8589380
2. [Protective effect of sodium bicarbonate in nitrite ion poisoning]Ukr Biokhim Zh (1978) · 1994 · PMID 7974833
3. Role of hypercapnia in brain oxygenation in sleep-disordered breathingActa Neurobiol Exp (Wars) · 2007 · PMID 17691228

More references from this article

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2. [The unknown physiological role of carbon dioxide]Fiziol Zh Im I M Sechenova · 1995 · PMID 7581542 · cited in Cholesterol, longevity, intelligence, and health
3. Differential effects of short-term hypoxia and hypercapnia on N-methyl-D-aspartate-induced cerebral vasodilatation in pigletsStroke · 1996 · PMID 8784141
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5. The role of epigenetics in aging and age-related diseasesAgeing Res Rev · 2009 · PMID 19716530
6. A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2Cell Metab · 2007 · PMID 17189204
7. [Changes in the sensitivity of leukocytes to the inhibiting effect of CO2 on their generation of active forms of oxygen in bronchial asthma patients]Ter Arkh · 1995 · PMID 7770796
8. Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMRProc Natl Acad Sci U S A · 1996 · PMID 8755523
9. The effects of partial chronic denervation on forearm metabolismCan J Neurol Sci · 1979 · PMID 487296
10. [New evidence for the inhibitory action of CO2 on generation of superoxide anion radicals by phagocytes in various tissues. (Mechanism of bio- and eco-effects of CO2)]Dokl Akad Nauk · 1996 · PMID 8924865
11. [Carbon dioxide gas inhibition of active forms of oxygen generation by cells in the internal organs and its biological significance]Biull Eksp Biol Med · 1996 · PMID 8829452
12. Acute respiratory alkalosis associated with low minute ventilation in a patient with severe hypothyroidismCan J Anaesth · 1999 · PMID 10084002 · cited in Bone Density: First Do No Harm
13. The structural modification of DNA nucleosides by nonenzymatic glycation: an in vitro study based on the reactions of glyoxal and methylglyoxal with 2'-deoxyguanosineAnal Bioanal Chem · 2008 · PMID 17965853
14. The epigenetic bottleneck of neurodegenerative and psychiatric diseasesBiol Chem · 2009 · PMID 19747081
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16. Glutamate and glutamine in the brain of the neonatal rat during hypercapniaArch Int Physiol Biochim · 1977 · PMID 71088