Ray Peat

Ray Peat on Sugar

By OxidativeState · · 62 articles · 46 studies

Short answer: Ray Peat argued that sugar is protective, not harmful. He wrote that sucrose and fruit lower stress hormones, support thyroid function and are less fattening than starch, and that the real dietary problems are polyunsaturated fat and excess starch.

What Ray Peat wrote about sugar

He rejected the idea that sugar causes diabetes. The belief started because diabetic urine tastes sweet, long before anyone knew the body can make sugar out of its own protein. Doctors then forbade sweets on ideology, not on evidence that it helped. Source: Sugar issues, Glucose and sucrose for diabetes

He tells the story of two 1860s doctors, Piorry in Paris and William Budd in England, who fed diabetics large amounts of sugar. One of Budd's patients got 8 ounces of white sugar and 4 ounces of honey a day, and the sugar in his urine went down. Source: Glucose and sucrose for diabetes, Sugar issues

He preferred sugar to starch. Starch and pure glucose strongly stimulate insulin, which pushes sugar into fat. Fructose restrains that insulin response, so ordinary sugar in place of starch reduces the tendency to store fat. Starch also stimulates the appetite. Source: Glycemia, starch, and sugar in context

He used the glycemic index against its own fans: orange juice and sucrose score lower than white bread or whole wheat bread. Source: Glycemia, starch, and sugar in context

He described sugar as anti-stress. Wild monkeys have low cortisol when their diet is mostly fruit, sucrose lowers the stress hormone ACTH, and he lists sugar among the things that reduce cortisol, adrenaline and free fatty acids. Source: Sugar issues, Lactate vs. CO2 in wounds, sickness, and aging; the other approach to cancer

He tied sugar to the thyroid. Turning T4 into the active T3 needs glucose, and the amount of T3 the liver makes depends mainly on how much glucose is available. Source: Glycemia, starch, and sugar in context, Glucose and sucrose for diabetes

He cites an animal experiment in which adding Coca-Cola, or the same amount of sucrose, let the animals eat 50% more calories without gaining more weight. Source: Glucose and sucrose for diabetes

He put conditions on it. Sugar is healthiest when it comes with minerals, as in milk and fruit. Refined white sugar is pure but has no nutrients, so he calls it a temporary therapeutic material or a substitute for when good fruit is not available. Source: Glucose and sucrose for diabetes, Sugar issues

What he suggested in practice

  • A daily diet with two quarts of milk and a quart of orange juice gives, in his words, enough sugar for general resistance to stress. More fruit juice or honey can help under heavier stress.
  • Orange juice at bedtime and before getting out of bed, because the blood becomes thicker and more clot-prone during the night.
  • For hypoglycemia he names orange juice, Coca-Cola or ice cream as things that can give great relief.
  • Fruit as a major part of the diet, and less starch from cereals and beans.

Where he wrote about it

This topic comes up in 62 of the articles on his site. These are the most relevant ones:

My take

This is the core of how I eat. I aim for 400 to 600 g of carbs a day, mostly simple sugars: fruit, juice, honey, Coke, table sugar. I have about 100 g of sugar with gelatin and salt in the first hour after waking.

If you are coming from keto, raise carbs slowly, 20 to 50 g per week. Your cells need time to re-learn how to burn glucose.

Quick answers

Did Ray Peat say sugar is healthy?

He wrote that sugar, especially from fruit, milk and honey, lowers stress hormones, supports thyroid function and is less fattening than starch. He also said refined sugar lacks nutrients and should be a supplement to a mineral-rich diet, not the base of it.

What did Ray Peat say about fructose?

He wrote that fructose restrains the insulin response to glucose, lowers phosphate, improves the retention of minerals such as magnesium and calcium, and he disputed the claim that fructose is to blame for fatty liver.

What did Ray Peat say about Coca-Cola?

He cites an animal study in which Coca-Cola or sucrose allowed 50% more calories without extra weight gain, and he names Coke, orange juice and ice cream as quick relief for hypoglycemia.

46 studies Ray Peat cited on sugar

  1. The effect of feeding different sugar-sweetened beverages to growing female Sprague-Dawley rats on bone mass and strengthBone · 2008 · PMID 18328797 · cited in Sugar issues
  2. Orange juice or fructose intake does not induce oxidative and inflammatory responseDiabetes Care · 2007 · PMID 17384340 · cited in Sugar issues
  3. Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucroseJ Med Food · 2004 · PMID 15117561 · cited in Sugar issues
  4. Comparison of the effects of sucrose and fructose on insulin action and glucose toleranceAm J Physiol Regul Integr Comp Physiol · 2000 · PMID 11004002 · cited in Sugar issues
  5. Sugars in diet and risk of cancer in the NIH-AARP Diet and Health StudyInt J Cancer · 2012 · PMID 21328345 · cited in Cancer: Disorder and Energy
  6. HPA axis dampening by limited sucrose intake: reward frequency vs. caloric consumptionPhysiol Behav · 2011 · PMID 21168428 · cited in Sugar issues
  7. An unexpected reduction in sucrose concentration activates the HPA axis on successive post shift days without attenuation by discriminative contextual stimuliPhysiol Behav · 2009 · PMID 19162053 · cited in Sugar issues
  8. Protective role of fructose in the metabolism of astroglial C6 cells exposed to hydrogen peroxideCarbohydr Res · 2009 · PMID 19591975 · cited in Sugar issues
  9. Luminal fructose inhibits rat intestinal sodium-phosphate cotransporter gene expression and phosphate uptakeAm J Clin Nutr · 2008 · PMID 18400728 · cited in Phosphate, activation, and aging
  10. Hepatic effects of a fructose diet in the stroke-prone spontaneously hypertensive ratAm J Hypertens · 2008 · PMID 18437120 · cited in Sugar issues
  11. Analgesia in preterm newborns: the comparative effects of sucrose and glucoseEur J Pediatr · 2007 · PMID 17203281 · cited in Sugar issues
  12. High rates of exogenous carbohydrate oxidation from a mixture of glucose and fructose ingested during prolonged cycling exerciseBr J Nutr · 2005 · PMID 15946410 · cited in Sugar issues
  13. Changes in lipid metabolism and antioxidant defense status in spontaneously hypertensive rats and Wistar rats fed a diet enriched with fructose and saturated fatty acidsNutrition · 2005 · PMID 15723754 · cited in Sugar issues
  14. Inclusion of low amounts of fructose with an intraportal glucose load increases net hepatic glucose uptake in the presence of relative insulin deficiency in dogAm J Physiol Endocrinol Metab · 2005 · PMID 15671083 · cited in Sugar issues
  15. The effects of drinks made from simple sugars on blood pressure in healthy older peopleBr J Nutr · 2005 · PMID 15975155 · cited in Salt, energy, metabolic rate, and longevity
  16. Reduction of endothelial NOS and bradykinin-induced extravasation of macromolecules in skeletal muscle of the fructose-fed rat modelCardiovasc Res · 2003 · PMID 14553836 · cited in Sugar issues, Glucose and sucrose for diabetes
  17. Sucrose ingestion normalizes central expression of corticotropin-releasing-factor messenger ribonucleic acid and energy balance in adrenalectomized rats: a glucocorticoid-metabolic-brain axis?Endocrinology · 2001 · PMID 11415998 · cited in Sugar issues, Glycemia, starch, and sugar in context
  18. Glucose or sucrose as an analgesic for newborns: a randomised controlled blind trialMinerva Pediatr · 2001 · PMID 11573063 · cited in Sugar issues
  19. Effect of sucrose on collagen metabolism in keloid, hypertrophic scar, and granulation tissue fibroblast culturesWorld J Surg · 2001 · PMID 11338013 · cited in Glucose and sucrose for diabetes
  20. Exercise-induced changes in brain glucose and serotonin revealed by microdialysis in rat hippocampus: effect of glucose supplementationActa Physiol Scand · 2001 · PMID 11683680 · cited in Tryptophan, serotonin, and aging
  21. Acute fructose administration decreases the glycemic response to an oral glucose tolerance test in normal adultsJ Clin Endocrinol Metab · 2000 · PMID 11134101 · cited in Sugar issues, Glycemia, starch, and sugar in context
  22. The interaction between dietary fructose and magnesium adversely affects macromineral homeostasis in menJ Am Coll Nutr · 2000 · PMID 10682873 · cited in Sugar issues
  23. Augmented resistance to oxidative stress in fatty rat livers induced by a short-term sucrose-rich dietBiochim Biophys Acta · 2000 · PMID 11018471 · cited in Glucose and sucrose for diabetes
  24. Effect of an amino acid on feeding preferences and learning behavior in the honey bee, Apis melliferaJ Insect Physiol · 2000 · PMID 10742528 · cited in Tryptophan, serotonin, and aging
  25. Influence of increase in osmotic pressure with sucrose on relaxation and cyclonucleotides levels in isolated rat aortaEur J Pharmacol · 1999 · PMID 10556668 · cited in Fatigue, aging, and recuperation
  26. Reduction of capillary permeability in the fructose-induced hypertensive ratAm J Hypertens · 1998 · PMID 9633792 · cited in Sugar issues
  27. [Fructose vs. glucose in total parenteral nutrition in critically ill patients]Anaesthesist · 1995 · PMID 8678268 · cited in Sugar issues
  28. In vivo and in vitro 31P magnetic resonance spectroscopic studies of the hepatic response of healthy rats and rats with acute hepatic damage to fructose loadingMagn Reson Med · 1994 · PMID 8015399 · cited in Phosphate, activation, and aging
  29. [Magnetic resonance imaging study on rat sugar cataract]Nippon Ganka Gakkai Zasshi · 1993 · PMID 8256667 · cited in Cataracts: water, energy, light, and aging
  30. Whole body and splanchnic oxygen consumption and blood flow after oral ingestion of fructose or glucoseAm J Physiol · 1993 · PMID 8476028 · cited in Sugar issues
  31. Metabolic effects of dietary sucrose in type II diabetic subjectsDiabetes Care · 1993 · PMID 8404438 · cited in Glycemia, starch, and sugar in context
  32. Diabetes-like action of intermittent fasting on sarcoplasmic reticulum Ca2+-pump ATPase and myosin isoenzymes can be prevented by sucroseBiochem Biophys Res Commun · 1989 · PMID 2529855 · cited in Heart and hormones
  33. Dietary fructose or starch: effects on copper, zinc, iron, manganese, calcium, and magnesium balances in humansAm J Clin Nutr · 1989 · PMID 2729168 · cited in Sugar issues
  34. Sucrose feeding prevents changes in myosin isoenzymes and sarcoplasmic reticulum Ca2+-pump ATPase in pressure-loaded rat heartBiochem Biophys Res Commun · 1988 · PMID 2973316 · cited in Heart and hormones
  35. Fructose prevents hypoxic cell death in liverAm J Physiol · 1987 · PMID 3631273 · cited in Sugar issues
  36. Synergistic improvement of glucose tolerance by sucrose feeding and exercise trainingAm J Physiol · 1986 · PMID 3521308 · cited in Sugar issues
  37. [Plasma glucose and C-peptide after ingestion of sucrose and starch in controlled insulin-dependent diabetics. Importance of glucose availability]Diabete Metab · 1984 · PMID 6489578 · cited in Sugar issues
  38. Short-term effects of various sugars on antinatriuresis and blood pressure changes in normotensive young menAm J Clin Nutr · 1983 · PMID 6344611 · cited in When energy fails: Edema, heart failure, hypertension, sarcopenia, etc
  39. Serum lipids and cholesterol distribution in lipoproteins of exercise-trained female rats fed sucroseLife Sci · 1983 · PMID 6345979 · cited in Sugar issues
  40. Effects of sucrose, caffeine, and cola beverages on obesity, cold resistance, and adipose tissue cellularityAm J Physiol · 1983 · PMID 6837766 · cited in Sugar issues, Glucose and sucrose for diabetes

Showing 40 of 46. Search all of them in the database →

Not affiliated with raypeat.com. This page describes Ray Peat's published articles in our own words and links to the originals. Educational content, not medical advice.

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